ParCC: Parameter Converter & Calculator for HTA

ParCC is an interactive Shiny application for Health Technology Assessment (HTA) parameter estimation. It bridges the gap between clinical evidence and economic models by automating complex parameter transformations with full formula documentation and literature citations.

Documentation: https://drpakhare.github.io/ParCC/

Installation

You can install ParCC from GitHub with:

# install.packages("remotes")
remotes::install_github("drpakhare/ParCC")

Quick Start

library(ParCC)
run_app()

Key Features

• Core Conversions – Rate to Probability, Odds to Probability, Time Rescaling, OR to RR (Zhang & Yu), Effect Size (Chinn).
• HR Converter – HR-to-probability, multi-HR comparison, NNT/NNH calculator, Log-rank to HR (Peto).
• Survival Extrapolation – Exponential, Weibull, and Log-Logistic fitting from published KM data.
• Background Mortality – SMR adjustment, Gompertz fitting, DEALE, linear interpolation.
• PSA Distributions – Beta, Gamma, LogNormal (Method of Moments), Dirichlet (multinomial).
• Economic Evaluation – ICER, Net Monetary Benefit, Value-Based Pricing (headroom analysis).
• Budget Impact Analysis – 5-year BIA framework with population uptake curves and discounting (ISPOR).
• PPP Currency Converter – Purchasing Power Parity conversion across 30 countries with WHO-CHOICE WTP thresholds.
• Global Currency Selector – INR, USD, EUR, GBP, JPY, and more; all economic modules update automatically.
• Batch Processing – Bulk rate, odds, and HR-based conversions with CSV upload/download.
• Lab Notebook – Generates an HTML report with methodology and citations for every session.

What’s New in v1.4.0

• Budget Impact Analysis (ISPOR framework)
• PPP Currency Converter with WHO-CHOICE WTP thresholds
• OR-RR and effect size conversions for NMA preparation
• NNT/NNH calculator and Log-rank to HR (Peto)
• Dirichlet distribution for Markov transition matrices
• Log-Logistic survival with non-monotonic hazard support
• Annuity / PV stream calculator
• Interactive clickable tool overview on Home page
• 5 new worked-example vignettes

Vignettes

After installation, browse the tutorials:

browseVignettes("ParCC")

Or visit the online documentation.

Citation

Regional Resource Centre for HTA, AIIMS Bhopal. (2025). ParCC: Parameter Converter & Calculator for Health Economic Evaluation (Version 1.4.0) [R package]. Available at: https://drpakhare.github.io/ParCC/