SmartPK: Automated Noncompartmental Pharmacokinetic Analysis
Provides functions for automated noncompartmental pharmacokinetic
(NCA) analysis using concentration-time data. The package estimates
pharmacokinetic parameters including area under the concentration-time
curve (AUC), area under the first moment curve (AUMC), maximum
concentration (Cmax), time to maximum concentration (Tmax),
terminal elimination rate constant (Kel), elimination half-life,
clearance, volume of distribution, and mean residence time (MRT).
It supports automatic terminal phase selection, bootstrap confidence
intervals, and publication-ready concentration-time profiles. Methods are
based on Gibaldi and Perrier (1982, ISBN:9780824710422).
Documentation:
Downloads:
Linking:
Please use the canonical form
https://CRAN.R-project.org/package=SmartPK
to link to this page.